The mismatch-repair proteins msh2 and msh6 interact with the imprinting control regions through the zfp57-kap1 complex

HIGHLIGHTS

• who: Basilia Acurzio from the Department of Environmental Biological and Pharmaceutical Sciences Vanvitelli”, Caserta, Italy have published the research: The mismatch-repair proteins MSH2 and MSH6 interact with the imprinting control regions through the ZFP57-KAP1 complex, in the Journal: (JOURNAL)
• what: The authors focused on the components of the mismatch-repair complex MSH2 and MSH6 and demonstrated their interactions with the ICRs by investigating their DNA binding profile by chromatin immunoprecipitation and sequencing. Using this approach, the authors showed that MSH6 was preferentially enriched on the maternal JF1 allele of the Plagl1 and Inpp5f . . .
  

   

  

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