The molecular basis of monopolin recruitment to the kinetochore

HIGHLIGHTS

  • who: Rebecca Plowman from the University of Edinburgh, Max Born Crescent, Edinburgh , BF, UK have published the Article: The molecular basis of monopolin recruitment to the kinetochore, in the Journal: (JOURNAL) of January/12,/2018
  • what: The authors show that both the complex subunit Csm1 and its binding site on the protein Dsn1 are broadly distributed throughout eukaryotes suggesting a conserved role in organisation and function. The authors demonstrate that both interfaces are required for robust monopolin recruitment to kinetochores and for sister kinetochore monoorientation, and that simultaneous disruption of both interfaces leads to additive . . .

     

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