HIGHLIGHTS
- who: Ugo Testa and colleagues from the Department of Oncology, Istituto Superiore di Sanitu00e0, Viale Regina Elena, Rome, Italy have published the research work: The Molecular Characterization of Genetic Abnormalities in Esophageal Squamous Cell Carcinoma May Foster the Development of Targeted Therapies, in the Journal: (JOURNAL)
- what: This analysis showed clear evidence of selection during clonal expansion in normal esophagi for the 74 genes investigated: dN/dS ratios for missense and protein-truncating mutations were 2.2 and 8.6, respectively, with the enrichment of non-synonymous mutations increasing rapidly with clone size . This study . . .
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