HIGHLIGHTS
- who: Takashi Ohtsuki from the DepartmentOkayama University, Tsushimanaka, Okayama, Japan have published the research work: The molecular mechanism of photochemical internalization of cell penetrating peptide-cargo-photosensitizer conjugates, in the Journal: Scientific Reports Scientific Reports
- what: In contrast, in this study, the authors examined a photosensitizer that was covalently linked to the carrier protein. If this study had been performed using unlinked photosensitizers, the authors could not have concluded that only the photoinduced 1O2 generation of the photosensitizers was important to effect endosomal escape of the cargo, because endosomal escape efficiency must also be affected . . .
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