The molecular ‘myc-anisms’ behind myc-driven tumorigenesis and the relevant myc-directed therapeutics

HIGHLIGHTS

  • who: Jessica McAnulty and Analisa DiFeo from the (UNIVERSITY) have published the research: The Molecular ‘Myc-anisms’ behind Myc-Driven Tumorigenesis and the Relevant Myc-Directed Therapeutics, in the Journal: (JOURNAL)
  • what: This approach has been adapted to a variety of targets, including the androgen receptor, estrogen receptor, BCL2, CDK9, and BET proteins to name a few .
  • future: Sammak et_al's high resolution crystal_structure of the Myc and Max heterodimer in the absence of DNA will aid in development of future Myc-targeting therapeutics . Studies aretransferase needed toactivity better . understand how this circular . . .

     

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