The monocytic cell line thp-1 as a validated and robust surrogate model for human dendritic cells

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  • who: Johanna Maria Hu00f6lken and Nicole Teusch from the Institute of Pharmaceutical Biology and Biotechnology, Heinrich-Heine University Du00fcsseldorf, Universitu00e4tsstrau00dfe, Du00fcsseldorf, Germany have published the research work: The Monocytic Cell Line THP-1 as a Validated and Robust Surrogate Model for Human Dendritic Cells, in the Journal: (JOURNAL)
  • what: The aim of this study was to generate robust, highly reproducible, and cost-effective protocols providing THP-1-derived iDC as well as mDC surrogates for in_vitro humanbased toxicological studies and for investigating the underlying mechanisms of sensitization and inflammation. To evaluate a conclusive differentiation of . . .

     

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