The monounsaturated fatty acid oleate is the major physiological toxic free fatty acid for human beta cells

HIGHLIGHTS

  • who: T Plötz from the (UNIVERSITY) have published the research: The monounsaturated fatty acid oleate is the major physiological toxic free fatty acid for human beta cells, in the Journal: Nutrition and Diabetes
  • what: The authors show in this study that the MUFA OA is not protective against PA-mediated toxicity to human beta cells.

SUMMARY

    Incubation medium in the final concentrations was prepared using DMEM medium with fatty_acid-free BSA10. Chemicals and media Free fatty_acids (FFAs) were purchased from SigmaAldrich (Munich, Germany). The branched-chain fatty_acid pristanic acid (PriA . . .

     

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