The motility of breast cancer cells is stimulated by hmgb1/rage interaction but the truncated form lacking the c terminus has no effect

HIGHLIGHTS

  • who: BioDiscovery and colleagues from the (UNIVERSITY) have published the paper: The motility of breast cancer cells is stimulated by HMGB1/RAGE interaction but the truncated form lacking the C terminus has no effect, in the Journal: (JOURNAL)
  • what: The authors investigated the effect of HMGB1 protein and its truncated form lacking the C terminus on the expression of endogenous RAGE in breast cancer cell lines (MCF7-noninvasive, MDA-MB-231-invasive) compared to normal breast epithelial one (MCF10).
  • how: The results showed that HMGB1 induced a migration of breast cancer cells and . . .

     

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