The multicellular effects of vdac1 n-terminal-derived peptide

HIGHLIGHTS

  • who: Uttpal Anand et al. from the Department of Life Sciences, Ben-Gurion University of the Negev, Medical University of Graz, Graz, Austria have published the research work: The Multicellular Effects of VDAC1 N-Terminal-Derived Peptide, in the Journal: Biomolecules 2022, 12, 1387. of 22/09/2022
  • how: The authors designed several cell-penetrating VDAC1 N-terminalderived peptides with the goal of identifying the shortest with improved cellular stability and activity. The VDAC1-based peptide R-Tf-D-LP4 was tested in several cancer types and found to simultaneously attack several hallmarks of cancer . . .

     

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