HIGHLIGHTS
- who: Zane Stekel and collaborators from the Department of Molecular and Cellular Biology, College of Biological Science, University of Guelph, Toronto, ON M J , Canada have published the paper: The Multifaceted Role of the Ubiquitin Proteasome System in Pathogenesis and Diseases, in the Journal: Biomolecules 2022, 12, 925. of /2022/
- what: This work provides new insights into the identification of novel E3 ligases for PROTACs design .
SUMMARY
Ubiquitination is a well-conserved protein post-translational modification (PTM), characterized by the covalent attachment of ubiquitin (Ub) or poly-Ub chains to substrate . . .
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