The murc ligase essential for peptidoglycan biosynthesis is regulated by the serine/threonine protein kinase pkna in corynebacterium glutamicum*

HIGHLIGHTS

  • who: Maria Fiuza from the (UNIVERSITY) have published the paper: The MurC Ligase Essential for Peptidoglycan Biosynthesis Is Regulated by the Serine/Threonine Protein Kinase PknA in Corynebacterium glutamicum*, in the Journal: (JOURNAL) of December/26,/2008
  • what: The authors extended the previous findings and demonstrated for the first time that PknA is able to specifically phosphorylate the essential murein ligase VOLUME 283.
  • how: MurC Phosphorylation Sites Are Critical for in Vitro and in Vivo Activity-The importance of the phosphorylation sites for MurC ligase activity was investigated in_vitro by site-directed_mutagenesis.
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