HIGHLIGHTS
- who: TYPE and collaborators from the Emory University, United States have published the paper: The mutation in splicing factor genes correlates with unfavorable prognosis, genomic instability, anti-tumor immunosuppression and increased immunotherapy response in pan-cancer, in the Journal: (JOURNAL)
- what: This analysis demonstrated that the SFG mutation was a significant, negative predictor of ratios of CD8+ T_cells/PD-1 (p=4.2 u00d7 10-8; u03b2=-.33). The authors comprehensively investigated associations of SFG mutations with clinical features, genomic integrity, anti-tumor immune_responses, and immunotherapy response in 12 common cancer types and their pan . . .
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