HIGHLIGHTS
- who: S Sampurno from the Department the University Melbourne, Parkville, Victoria, Australia have published the article: The Myb-p300-CREB axis modulates intestine homeostasis, radiosensitivity and tumorigenesis, in the Journal: (JOURNAL)
- how: In this study an inducible creb knockout (KO) model was used to define the role of CREB in the GI of adult mice in proliferation and differentiation under homeostasis and stress. To extend this analysis further the authors also employed an antibody against a more distantly related TF ATF2 .
SUMMARY
Multiple external stimuli induce CREB activation via several kinase . . .
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