The n terminus of a schistosome ù² subunit regulates inactivation and current density of a cav2 channel*

HIGHLIGHTS

• who: Vicenta Salvador-Recatalà from the Vicenta Salvador-Recatalà, and Robert MGreenberg From the Department of Pathobiology, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania , The ␤ subunit of high voltage-activated Ca2ⴙ (Cav) channels targets the pore-forming ␣, subunit to the plasma membrane and tunes the biophysical phenotype of the Cav channel complex. We used a combination of molecular biology and wholecell patch clamp to investigate the functional role of a long, terminal polyacidic motif (NPAM) in a Cav␤ subunit of the human parasite Schistosoma mansoni (␤Sm), a motif that does not occur in other known . . .
  

   

  

  If you want to have access to all the content you need to log in!

  Thanks :)

  Username or E-mail:

  If you don't have an account, you can create one here.