The nadph oxidase nox4 controls macrophage polarization in an nf κ b-dependent manner

HIGHLIGHTS

• who: V. Helfinger and collaborators from the Institute for Cardiovascular Physiology, Goethe-University, Frankfurt, Germany have published the article: The NADPH Oxidase Nox4 Controls Macrophage Polarization in an NF κ B-Dependent Manner, in the Journal: Oxidative Medicine and Cellular Longevity of 18/04/2019
• what: The authors show that macrophages besides a high level of Nox2 indeed express Nox4. The authors provide evidence that Nox4 deficiency prevents STAT6 phosphorylation and supports NFκB activation.

SUMMARY

Although, there is evidence that Nox4 is expressed in macrophages, this is rather inconsistent throughout the . . .

 



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