HIGHLIGHTS
- who: Feng Qian from the (UNIVERSITY) have published the article: The Nanomechanics of Polycystin-1 Extracellular Region*, in the Journal: (JOURNAL) of October/11,/2005
- how: Recent data indicated that PC1 may function as a cell adhesion receptor involved in cell-cell or cell-matrix interactions .
SUMMARY
PC1 is a large (⬃520 kDa) membrane protein with an extensive N-terminal extracellular portion, comprising some 3,000 amino_acids (Fig 1). Indeed a recent study demonstrated that the first five PKD domains have remarkably high mechanical stability, suggesting that the PC1 extracellular domain . . .
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