The negative feedback-loop between the oncomir mir- 24-1 and menin modulates the men1 tumorigenesis by mimicking the ‘‘knudson’s second hit’’

HIGHLIGHTS

• who: Ettore Luzi et al. from the Metabolic Bone Unit, Department of Internal Medicine, University of Florence, Florence, Italy have published the paper: The Negative Feedback-Loop between the Oncomir Mir- 24-1 and Menin Modulates the Men1 Tumorigenesis by Mimicking the ‘‘Knudson’s Second Hit’’, in the Journal: (JOURNAL) of June/27,/2012
• what: The authors analyzed the expression profile of miR24-1 in parathyroid adenomas from MEN1 patients, with different MEN1 mutations, in which the main difference was the MEN1 LOH or the maintenance of the wild_type MEN1 allele. The authors showed that . . .
  

   

  

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