HIGHLIGHTS
SUMMARY
Some amphoteric molecules with a minor positive charge, such as albumin, are also capable of binding to glycocalyx components (Pries et_al, 2000; Reitsma et_al, 2007; Becker et_al, 2010). Overexpression of some glycoproteins, for example, Mucin 1, correlates with the development of aggressive cancers (Knelson et_al, 2014; Mitchell and King, 2014; Paszek et_al, 2014; Mallard and Tiralongo, 2017; Barnes et_al, 2018; Kuo et_al, 2018; Vitale et_al, 2019; Ahrens et_al, 2020). Collagen-like domains are found in the structure of proteoglycans of the glycocalyx and class A scavenger receptors (Muñoz and Linhardt, 2004; Ori et_al . . .
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