The new microtubule-targeting agent six2g induces immunogenic cell death in multiple myeloma

HIGHLIGHTS

  • who: Katia Grillone and collaborators from the Department of Experimental and Clinical Medicine, Magna Graecia University of Catanzaro, Catanzaro, Italy have published the paper: The New Microtubule-Targeting Agent SIX2G Induces Immunogenic Cell Death in Multiple Myeloma, in the Journal: (JOURNAL)
  • what: In the docking simulations, the authors focused the attention on the RVxF PP1 domain and observed that SIX2G exhibited G-score values comparable to that of known active compounds in all 3D models of the RVxF domain . The authors report the development, preclinical validation and characterization of SIX2G, a novel small_molecule belonging to . . .

     

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