HIGHLIGHTS
- who: Sonia Kiran from the Department of Pharmaceutical Sciences, College of Pharmacy, University of Tennessee Health Science Center (UTHSC), Memphis, TN, United States have published the article: The NLRP3 Inflammasome Inhibitor Dapansutrile Attenuates Cyclophosphamide-Induced Interstitial Cystitis, in the Journal: (JOURNAL)
- what: The authors demonstrated that inhibiting NLRP3 using Dap reduced the IC disease score, level of systemic cytokines, infiltration of T_cells, mast cells, neutrophils, and mediating DCs in the UB, thereby ameliorating the severity of IC. The authors report decreased levels of TNF-a, IL-17, IP-10, IL-1B, RANTES, MCP-1, IL . . .
If you want to have access to all the content you need to log in!
Thanks :)
If you don't have an account, you can create one here.