The nmr signature of gluconoylation: a frequent n-terminal modification of isotope-labeled proteins

HIGHLIGHTS

  • who: David Schweida from the Department of Biosciences, University of Salzburg, Billrothstr11, Salzburg, Austria have published the paper: The NMR signature of gluconoylation: a frequent N-terminal modification of isotope-labeled proteins, in the Journal: (JOURNAL)
  • what: The authors show that the can hydrolyze over time resulting in a free and gluconate.

SUMMARY

    Post-translational protein modifications (PTMs) add another layer of complexity to the proteome and each modification can potentially change the structure, function and stability of a protein (Aebersold et_al 2018). N-terminal gluconoylation and phosphogluconoylation were first noticed . . .

     

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