The novel compound sul-138 counteracts endothelial cell and kidney dysfunction in sepsis by preservingmitochondrial function

HIGHLIGHTS

  • who: Bastiaan S. Star and colleagues from the Department of Clinical Pharmacy and Pharmacology, University Medical Center Groningen, RB Groningen, The Netherlands have published the paper: The Novel Compound SUL-138 Counteracts Endothelial Cell and Kidney Dysfunction in Sepsis by PreservingMitochondrial Function, in the Journal: (JOURNAL)
  • what: The authors explored the efficacy of the novel protective compound SUL-138 in sepsis models in HUVECs and mice. The authors show that treatment with SUL-138 supports mitochondrial function of LPS-stimulated endothelial cells and in the kidney of septic mice. By capturing crucial disease features of . . .

     

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