HIGHLIGHTS
- who: Chen-Ting Hung from the (UNIVERSITY) have published the research: The novel role of ER protein TXNDC5 in the pathogenesis of organ fibrosis: mechanistic insights and therapeutic implications, in the Journal: (JOURNAL)
- what: Emerging evidence has demonstrated the essential role of TXNDC5 in organ fibrogenesis by inducing fibroblast activation, proliferation and ECM production through its PDI activity.
SUMMARY
Fibrosis, a non-physiological repair process in multiple organs, occurs in response to chemical, immunological and physical insults, evolutionarily designed as the body`s matrix synthetic machinery to repair and maintain tissue . . .
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