The olfactory bulb coordinates the ventral hippocampus-medial prefrontal cortex circuit during spatial working memory performance

HIGHLIGHTS

SUMMARY

    Although previous studies have investigated the significance of OB in cognitive performance and its interaction with the activity of distant brain areas, the communication of OB with the vHPC-mPFC circuit during working memory performance is not elucidated yet. Given rich anatomical connections between OB, mPFC, and vHPC structures, and considering previous evidence regarding the role of OB activities on synchronized brain activities in cognitive performance, the authors hypothesized that OB could modulate vHPC-mPFC circuit activity during spatial working memory task performance. MPFC Filtered LFP and amp;lt; 4 Hz 0.12 Correct . . .

     

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