The pharmacokinetics of continuous subcutaneous levodopa/carbidopa infusion: findings from the nd0612 clinical development program

HIGHLIGHTS

  • who: Peter A. LeWitt from the Toulouse, France Sapienza University of Rome, Italy have published the paper: The pharmacokinetics of continuous subcutaneous levodopa/carbidopa infusion: Findings from the ND0612 clinical development program, in the Journal: (JOURNAL)
  • what: The studies also explored augmenting the SC administration of ND0612 with oral levodopa/carbidopa, administered either alone or in combination with the COMT inhibitor entacapone.
  • how: These studies were conducted in healthy volunteers and in PD patients experiencing an established pattern of motor fluctuations while on their current regimen of levodopa and an inhibitor of aromatic . . .

     

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