The pharmacological effects of phenylephrine are indirect, mediated by noradrenaline release from the cytoplasm

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• who: Mahmoud Al-Khrasani from the Animals Male NMRI mice (35, g) were purchased from Toxicoop Zrt(Budapest, Hungary) and their vas deferens was used for recording contractions. Male , mice weighing, g were obtained from Charles River (Budapest, Hungary) and housed in a local animal facility and used for release experiments. Animals were kept in groups in a temperature- and humidity-controlled room under a, h light/dark cycle and under standard conditions of laboratory animal housing. The experiments followed the guidelines of the Ethical Board of Semmelweis University (EC Directive, EU). The Semmelweis University Regional and . . .
  

   

  

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