The pharmacologically active alkaloid cryptolepine activates a type 1 interferon response that is independent of mavs and sting pathways

HIGHLIGHTS

  • who: STING Pathways and collaborators from the West African Centre for Cell Biology of Infectious Pathogens, University of, Department of Microbial Sciences, University of Surrey, Guildford, UK have published the research work: The Pharmacologically Active Alkaloid Cryptolepine Activates a Type 1 Interferon Response That Is Independent of MAVS and STING Pathways, in the Journal: Journal of Immunology Research of 26/07/2022
  • what: The authors report for the first time that cryptolepine a pharmacoactive alkaloid in the medicinal plant Cryptolepis sanguinolenta is a potent IFN-1 pathway inducer.
  • how: The data were analysed . . .

     

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