The phosphodiesterase 5 inhibitor sildenafil decreases the proinflammatory chemokine il-8 in diabetic cardiomyopathy: in vivo and in vitro evidence

HIGHLIGHTS

• who: S. Giannattasio from the Department of Movement, Human and Health Sciences, Section of Health Sciences, Unit of Endocrinology, Università degli Studi di Roma "Foro Italico", Rome, Italy Institute for Cancer Genetics, University of Columbia, New York, USA have published the research: The phosphodiesterase 5 inhibitor sildenafil decreases the proinflammatory chemokine IL-8 in diabetic cardiomyopathy: in vivo and in vitro evidence, in the Journal: (JOURNAL)
• what: Considering the pivotal role of IL-8 during inflammation-induced tissue/cell damage in cardiac diseases, herein the authors aim to investigate whether sildenafil can target IL-8 . . .
  

   

  

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