HIGHLIGHTS
- who: Pin Zhao from the (UNIVERSITY) have published the paper: The phosphorylation to acetylation/methylation cascade in transcriptional regulation: how kinases regulate transcriptional activities of DNA/histone-modifying enzymes, in the Journal: (JOURNAL)
- how: This review describes how phosphorylation affects the of these enzymes other functions including protein stability subcellular localization binding to chromatin interaction with other proteins.
SUMMARY
Stability, cellular localization, protein/DNA binding, and enzymatic activity. In general, TFs firstly occupy DNA elements in a sequence-specific manner, and then recruit the RNA_polymerases to the gene`s promoter region . . .
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