The pituitary adenylate cyclase-activating polypeptide (pacap) system of the central amygdala mediates the detrimental effects of chronic social defeat stress in rats

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  • who: Significance Statement et al. from the Laboratory of Addictive Disorders, Departments of Pharmacology and Psychiatry, Boston University School of have published the paper: The Pituitary Adenylate Cyclase-Activating Polypeptide (PACAP) System of the Central Amygdala Mediates the Detrimental Effects of Chronic Social Defeat Stress in Rats, in the Journal: (JOURNAL)
  • what: A limitation of this study is that it was performed exclusively in male subjects because historically the CSDS model was developed in males; future studies will be needed to determine either the generalizability or the selectivity of the effects using female animals.
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