The pleckstrin homology domains of phospholipases c-β and -δ confer activation through a common site*

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  • who: Yuanjian Guo from the (UNIVERSITY) have published the Article: The Pleckstrin Homology Domains of Phospholipases C-β and -δ Confer Activation through a Common Site*, in the Journal: (JOURNAL) of February/10,/2003
  • what: The aim of this latter construct was to test whether altering this linker and EF hand would affect the interaction between the PH domain and the catalytic core. In Fig 2a the authors show the association of PLC␤2, PLC␦1, and the PH␦PLC␤ chimera to POPC bilayers. Because the studies compare the affinities between the PLC enzymes and G protein . . .

     

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