HIGHLIGHTS
- who: Sadaf Ashraf from the School of Pharmacy, University of Nottingham, Nottingham, UK School of Life Sciences, University of have published the paper: The polyadenylation inhibitor cordycepin reduces pain, inflammation and joint pathology in rodent models of osteoarthritis, in the Journal: Scientific Reports Scientific Reports of 15/02/2019
- what: The authors demonstrate an increased expression of polyadenylation factor CPSF4 associated with synovial inflammation in human OA and that the polyadenylation inhibitor cordycepin sequestered polyadenylation factors in the cytoplasm of human macrophages, reducing nuclear levels of polyadenylation factors. The authors demonstrate that the effects of . . .
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