The potential for placental activation of ppar to improve the angiogenic profile in preeclampsia

HIGHLIGHTS

  • who: Brooke Grimaldi and colleagues from the Department of Obstetrics, Gynecology and Reproductive Biology, College of Human Medicine, Michigan State University, Grand Rapids, MI, USA have published the article: The Potential for Placental Activation of PPAR to Improve the Angiogenic Profile in Preeclampsia, in the Journal: Cells 2022, 11, 3514. of /2022/
  • what: The authors report novel findings of PPARu03b3 actions in the placenta which have dramatic indirect effects on the endothelium.
  • how: While the data is not statically significant it does follow a pattern of reduced PlGF secretion from the PE placenta . . .

     

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