The potential protective effect and underlying mechanisms of physiological unconjugated hyperbilirubinemia mediated by ugt1a1 antisense oligonucleotide therapy in a mouse model of cyclosporine a-induced chronic kidney disease

HIGHLIGHTS

  • who: Basma H. Marghani and colleagues from the Department of Physiology, Faculty of Veterinary Medicine, Mansoura University, Mansoura, Egypt Abha, Saudi Arabia have published the paper: The Potential Protective Effect and Underlying Mechanisms of Physiological Unconjugated Hyperbilirubinemia Mediated by UGT1A1 Antisense Oligonucleotide Therapy in a Mouse Model of Cyclosporine A-Induced Chronic Kidney Disease, in the Journal: Metabolites 2022, 12, x FOR PEER REVIEW of /2022/
  • what: Subsequently, this study aimed to investigate whether physiological unconjugated hyperbilirubinemia induced by UGT1A1 antisense morpholinos protects against the progression of CKD in a mice model of cyclosporine A . . .

     

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