The potential therapeutic role of extracellular vesicles in osteoarthritis

HIGHLIGHTS

  • who: EV engineering and collaborators from the Chongqing University, China have published the research work: The potential therapeutic role of extracellular vesicles in osteoarthritis, in the Journal: (JOURNAL)
  • how: He et_al treated OA rats with BMSC-EVs and the results indicated that BMSC-EVs improved chondrocyte phenotype and alleviated pain via ameliorating function of dorsal root ganglion (DRG).

SUMMARY

    Osteoarthritis (OA) is a worldwide and disabling disease, which cause severe pain and heavy socioeconomic burden (Glyn-Jones et_al, 2015). Aging-related cell senescence, metabolic disorder and aberrant mechanical load can lead . . .

     

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