The prion-like transmission of tau oligomers via exosomes

HIGHLIGHTS

  • who: Diana L. Castillo-Carranza from the University of Texas Medical Branch at Galveston, United States have published the Article: The prion-like transmission of tau oligomers via exosomes, in the Journal: (JOURNAL)

SUMMARY

    Tauopathies, such as Alzheimer`s disease (AD) and Parkinson`s disease dementia (PDD), are neurodegenerative disorders involving the spread of toxic forms of tau protein, resulting in characteristic aggregates and cytoplasmic inclusions that impair normal neuronal functioning (Irwin et_al, 2013; Shi et_al, 2016; Orr et_al, 2017; Polanco et_al, 2018b). In normal states, tau`s primary function is to stabilize . . .

     

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