The prognostic implications and tumor-promoting functions of chsy3 in gastric cancer

HIGHLIGHTS

• What: High CHSY3 expression was associated with poor patient prognosis, and the experiments showed that CHSY3 expression regulated the proliferation and migration of gastric cancer cells, and increased the infiltration of tumor-associated macrophages. CHSY3 expression was associated with a favorable outcome in GC patients, and this study showed that increased CHSY3 expression was linked to a worse prognosis in the TCGA GC cohort (OS: HR=1.58, p=0.007; DSS: HR=1.54, p=0.046) . In this paper, the role of CHSY3 in gastric cancer was shown to be related to the malignant phenotype . . .
  

   

  

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