The prophylactic effects of monoclonal antibodies targeting the cell wall pmt4 protein epitopes of candida albicans in a murine model of invasive candidiasis

HIGHLIGHTS

  • who: Bing Han and Lan Yan from the China University Of Delhi have published the article: The prophylactic effects of monoclonal antibodies targeting the cell wall Pmt4 protein epitopes of Candida albicans in a murine model of invasive candidiasis, in the Journal: (JOURNAL)
  • what: The authors focused on the potential prophylactic value of mAbs C12 and C346 in a disseminated candidiasis murine model.
  • future: Investigation of the binding profiles to other pathogenic fungi is needed to be validated.

SUMMARY

    Of note, protein mannosyltransferase (Pmt4), encoding mannosyltransferases initiating O-mannosylation . . .

     

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