The protease inhibitor hai-2, but not hai-1, regulates matriptase activation and shedding through prostasin*

HIGHLIGHTS

  • who: Stine Friis from the (UNIVERSITY) have published the research: The Protease Inhibitor HAI-2, but Not HAI-1, Regulates Matriptase Activation and Shedding through Prostasin*, in the Journal: (JOURNAL) of April/15,/2014
  • what: This analysis showed that St14 mRNA levels were not different in mice of the three genotypes, suggesting that endogenous HAI-2 regulates endogenous matriptase expression at the translational or post-translational level. This study directly examined the role of endogenous HAI-1 and HAI-2 in regulating endogenous matriptase trafficking and activation in polarized epithelium of the large and small . . .

     

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