The proteasome regulator rpn4 controls antifungal drug tolerance by coupling protein homeostasis with metabolic responses to drug stress

HIGHLIGHTS

• who: Ka Pui Sharon Yau and colleagues from the Monash University, Clayton, Victoria, Australia, Centre to Impact AMR, Monash University, Clayton have published the article: The proteasome regulator Rpn4 controls antifungal drug tolerance by coupling protein homeostasis with metabolic responses to drug stress, in the Journal: (JOURNAL) of April/19,/2023
• what: The authors report that the transcriptional activator Rpn4 is important for drug tolerance in the human fungal pathogen Candida albicans. Based on the findings the authors propose that Rpn4 is a central hub for fluconazole tolerance in C. albicans by coupling the regulation . . .
  

   

  

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