HIGHLIGHTS
- who: Lei Yang from the University, China have published the article: The protective role of EP300 in monocrotaline-induced pulmonary hypertension, in the Journal: (JOURNAL)
- what: The authors aimed to explore the mechanism of this potential relationship. The work has shed light on the role of EP300 upregulation in MCT-induced PH, which may be a compensation mechanism to prevent the further deterioration of the disease. To summarize, this work reveals that EP300 expression is increased in the MCT-induced PH model mediated by EGR1, and EP300 has the potential to provide protection from PAH . . .
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