The protein kinase r modifies gut physiology to limit colitis

HIGHLIGHTS

  • who: Howard Chi Ho Yim et al. from the Weizmann Institute of Science, Israel Duke University, United States have published the research: The protein kinase R modifies gut physiology to limit colitis, in the Journal: (JOURNAL)
  • what: This activity is largely but not entirely dependent on substrate phosphorylation. description and subsequent measures , it was reported that the mutated Eif2ak2 locus retained expression of a truncated kinase domain . These findings partly reconcile the previous discrepant findings and endorses a different mechanism of action for PKR in colitis than was asserted in the earlier studies by Cao . . .

     

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