The pursuit of the “inside” of the amyloid hypothesis—is c99 a promising therapeutic target for alzheimer’s disease?

HIGHLIGHTS

  • who: Nobumasa Takasugi and collaborators from the Department of Medicinal Pharmacology, Graduate School of Medicine, and, Okayama University, Okayama, Japan have published the paper: The Pursuit of the u201cInsideu201d of the Amyloid Hypothesisu2014Is C99 a Promising Therapeutic Target for Alzheimeru2019s Disease?, in the Journal: Cells 2023, 12, x FOR PEER REVIEW of /2023/
  • what: Although this review focuses on Au03b2 and C99, other metabolic to AD pathogenesis have been investigated in detailand . mechanisms of APP, such as u03b4-secretase u03b7-secretase cleavage, and their contribution to AD pathogenesis have been investigated in detail . promoting Swedish . . .

     

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