HIGHLIGHTS
SUMMARY
The international scientific community was put in the situation to react promptly and efficiently, rapidly engaging in unprecedented research efforts, to accelerate the clinical studies needed to uncover the pathophysiology of the severe acute respiratory disease coronavirus 2 (SARS-CoV-2) infection. As the results could not be repeated by other scientists, it needed to be rediscovered in the 1930s. When blood pressure drops, the cells of the macula densa (also a component of the juxtaglomerular apparatus) sense the decrease of the Na+ concentration, and in response produce a number of paracrine mediators that . . .
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