The relationship between hmgb1 and autophagy in the pathogenesis of diabetes and its complications

HIGHLIGHTS

  • who: Kun Yang and collaborators from the Yale University, United States have published the research: The relationship between HMGB1 and autophagy in the pathogenesis of diabetes and its complications, in the Journal: (JOURNAL)
  • how: The results showed that 50 mg/kg astilbin reduced infarct volume improved hemodynamics reduced myocardial injury and decreased serum proinflammatory factor levels. The results showed that GLP-1RA effectively reduced fasting blood glucose (FBG) total cholesterol (TC) triglyceride (TG) and malondialdehyde (MDA) levels in mice.
  • future: The exact mechanism of action is still unclear and further experimental studies are . . .

     

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