The relationship of alpha-synuclein to mitochondrial dynamics and quality control

HIGHLIGHTS

  • who: David A. Tumbarello from the Stockholm University, Sweden Griffith University, Australia have published the research: The relationship of alpha-synuclein to mitochondrial dynamics and quality control, in the Journal: (JOURNAL)

SUMMARY

    Consequently, dysfunctional mitochondria have been associated with the pathogenesis of several neurodegenerative diseases, including Alzheimer`s disease (AD), Parkinson`s disease (PD), Huntington`s disease (HD), and amyotrophic lateral sclerosis (ALS) (Beal, 2005; Reddy and Beal, 2008; Muyderman and Chen, 2013; Franco-Iborra et_al, 2018). During aging, both respiratory capacity and ATP production are reduced in mitochondria, which is coupled to . . .

     

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