The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets

HIGHLIGHTS

• who: Kezia C. L. Whatley and collaborators from the Editor: TLoVerde, University of Texas Cardiff, United Kingdom have published the research work: The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets, in the Journal: (JOURNAL) of October/30,/2019
• what: The authors describe a repositioning strategy to assess the anthelmintic activity of epigenetic probes/ inhibitors obtained from the Structural Genomics Consortium.
• how: Following on from this comparative sequence analysis a single-point (10 μM) schistosomula screen of these 37 compounds was implemented to assess their anthelmintic properties . . .
  

   

  

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