HIGHLIGHTS
- who: Jonathan Parkinson from the (UNIVERSITY) have published the Article: The RESP AI model accelerates the identification of tight-binding antibodies, in the Journal: (JOURNAL) of 31/07/2022
- what: The authors develop a learned representation trained on over 3 million human B-cell receptor sequences to encode antibody sequences. The authors demonstrate the power of this pipeline by achieving a 17-fold improvement in the KD of the PD-L1 antibody Atezolizumab and this success illustrates the potential of RESP in facilitating general antibody development. The authors show this learned representation enables more efficient . . .
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