The retinoblastoma tumor suppressor regulates a xenobiotic detoxification pathway

HIGHLIGHTS

  • who: The Retinoblastoma, Tumor Suppressor and Xenobiotic Detoxification, Pathway from the Department of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America, Department of Molecular Virology, Immunology and have published the research: The Retinoblastoma Tumor Suppressor Regulates a Xenobiotic Detoxification Pathway, in the Journal: (JOURNAL) of October/12,/2011
  • what: In this report the authors show that both pRb and its interacting partners transcriptional factors E2F1-2-3 act as positive modulators of pathways important for metabolizing and clearing xenobiotics-such as toxins and drugs-from body. The authors focused on probes for . . .

     

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