The ring finger protein family in health and disease

HIGHLIGHTS

  • who: Chunmei Cai from the (UNIVERSITY) have published the Article: The RING finger protein family in health and disease, in the Journal: (JOURNAL) of 21/04/2022
  • what: Impaired B-cell anergy to self-antigen is observed in B cell-specific Cbl-dko mice, leading to impaired B-cell tolerance, which may be one of the major reasons contributing to the pathogenesis of the SLE-like autoimmune disease. This study provided a novel negative_feedback regulation of RIG-I-mediated antiviral innate immunity through PTM of RIG-I. This study provided a potential target at RNF198 . . .

     

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